Expression of S100A11 in bulk pancreatic tissues (pancreatic cancer, n = 22; IPMN, n = 18; nonneoplastic pancreas, n = 22). Expression of S100A11 in bulk.

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Expression of S100A11 in bulk pancreatic tissues (pancreatic cancer, n = 22; IPMN, n = 18; nonneoplastic pancreas, n = 22). Expression of S100A11 in bulk pancreatic tissues (pancreatic cancer, n = 22; IPMN, n = 18; nonneoplastic pancreas, n = 22). Total RNA (10 ng) extracted from snap-frozen tissues was used for analysis of S100A11 expression by real-time RT-PCR. β-Actin was used as a reference gene. Pancreatic cancer (median, 2.40) and IPMN bulk tissues (median, 2.04) expressed significantly higher levels of S100A11 than did nonneoplastic bulk pancreatic tissues (median, 0.97; pancreatic cancer versus nonneoplastic pancreas, P < 0.0001; IPMN versus nonneoplastic pancreas, P < 0.0001). S100A11 expression did not differ significantly between pancreatic cancer and IPMN bulk tissues. Kenoki Ohuchida et al. Clin Cancer Res 2006;12:5417-5422 ©2006 by American Association for Cancer Research