Association between the location of transposed ovary and ovarian function in patients with uterine cervical cancer treated with (postoperative or primary)

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Association between the location of transposed ovary and ovarian function in patients with uterine cervical cancer treated with (postoperative or primary) pelvic radiotherapy Jong Ha Hwang, M.D., Ph.D., Heon Jong Yoo, M.D., Sae Hyun Park, M.D., Myong Cheol Lim, M.D., Ph.D., Sang-Soo Seo, M.D., Ph.D., Sokbom Kang, M.D., Ph.D., Joo-Young Kim, M.D., Ph.D., Sang-Yoon Park, M.D., Ph.D. Fertility and Sterility Volume 97, Issue 6, Pages 1387-1393.e2 (June 2012) DOI: 10.1016/j.fertnstert.2012.02.052 Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The roentgenogram of a patient who underwent ovarian transposition that shows the metallic clips in kidneys, ureters, and bladder. The perpendicular distance (bidirectional arrow) between the clip (white arrow) of the lower border of the ovary and the horizontal line (white line) of iliac crest was used to evaluate the cutoff point for preserving normal function of the transposed ovary. Fertility and Sterility 2012 97, 1387-1393.e2DOI: (10.1016/j.fertnstert.2012.02.052) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Figure 2 The receiver operator characteristic (ROC) curve and location of the transposed ovary in the 31 patients who received primary or adjuvant radiotherapy. (A) ROC and ROC area under the curve values were 0.757 (95% confidence interval 0.572–0.943). The best cutoff value was 1.5 cm above the iliac crest (P<.022). (B) Distribution of the lower clip in the higher located ovary. The solid line denotes the level of the iliac crest and the dashed line indicates 1.5 cm above the iliac crest. Fertility and Sterility 2012 97, 1387-1393.e2DOI: (10.1016/j.fertnstert.2012.02.052) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Classification according to the type of operation in the patients who underwent ovarian transposition (N = 53). RT = radiotherapy. Fertility and Sterility 2012 97, 1387-1393.e2DOI: (10.1016/j.fertnstert.2012.02.052) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Classification according to adjuvant radiotherapy and presence of ovarian function in the patients who underwent ovarian transposition (N = 53). Group 1, patients who received adjuvant radiotherapy and normal ovarian function; group 2, patients who received adjuvant radiotherapy and were in menopausal state; group 3, patients who did not receive adjuvant radiotherapy. Fertility and Sterility 2012 97, 1387-1393.e2DOI: (10.1016/j.fertnstert.2012.02.052) Copyright © 2012 American Society for Reproductive Medicine Terms and Conditions