Tuberculosis in Wales Annual Report 2017 Data to the end of 2016 Communicable Disease Surveillance Centre, Health Protection, Public Health Wales, Cardiff, UK

Number of cases and rate of TB per 100,000 population, Wales, 2007-2016

Rate of TB per 100,000 population in the UK, 2016

Rate of TB per 100,000 population by Local Authority, Wales a) 2016 b)2012-2016 © Crown Copyright and database right 2014. Ordnance Survey 100044810

Rate of TB per 100,000 population by age group and year, Wales, 2007-2016

Average annual number of TB cases and rate per 100,000 population by ethnic group, Wales, 2012-2016 Rates for ethnic groups were calculated using ONS 2011 population estimates for ethnic groups resident in Wales

Number of non-UK born TB cases, Wales, 2007-2016 During 2007-2016 between 1-13% of cases were reported with an unknown origin for place of birth.

History of or current social risk factors among TB patients, Wales, 2012-2016

Rate of TB per 100,000 population by deprivation quintile, Wales, 2016 The 2014 Welsh Index of Multiple Deprivation (WIMD) was used to assign cases to deprivation fifth using postcode of residence and Lower Super Output Area (LSOA). Rates by deprivation fifth were calculated using ONS 2014 population estimates for LSOAs. Deprivation scores from the 2014 index are not comparable to previous indices. The WIMD is an ecological measure and not all deprived people live in deprived areas and not all people in deprived areas are deprived.

Number and percentage of TB cases by site of disease, Wales, 2012-2016 Patients may have disease at more than one site Pulmonary TB includes miliary TB in accordance with the WHO’s recommendation and international reporting definitions. Revised trends in site of disease are presented for previous years using the revised WHO definitions.

Number and percentage of TB cases with bacteriological confirmation, Wales, 2012-2016 Denominator for percentage culture confirmed is total number of TB cases. Denominator for percentage of pulmonary cases culture confirmed is total number of pulmonary TB cases. Denominator for percentage of positive sputum smear pulmonary cases is the number of pulmonary cases with sputum smear taken. 1Denominator for percentage culture confirmed is total number of TB cases. 2Denominator for percentage of pulmonary cases culture confirmed is total number of pulmonary TB cases. 3Denominator for percentage of positive sputum smear pulmonary cases is the number of pulmonary cases with sputum smear taken.

Species identification in culture confirmed TB cases, Wales, 2012-2016

Number and proportion of TB cases with first line drug resistance, Wales, 2007-20161 1 Includes culture confirmed cases with drug susceptibility results for at least isoniazid and rifampicin 2 Excludes M. bovis cases

TB treatment outcome at 12 months for drug sensitive cases with expected treatment duration <12 months, Wales, 2015 Excludes initial and amplified to rifampicin resistant TB and MDR-TB cases and MDR-TB treated cases and those with CNS, spinal, miliary or cryptic disseminated TB. Not evaluated includes missing, unknown and transferred out. As treatment outcomes are reported at 12 months, treatment outcomes are only available to be reported on for cases notified in the previous year, at the time data are extracted for the report.

Last recorded TB treatment outcome for the entire drug sensitive cohort, Wales, 2015 Excludes initial and amplified to rifampicin resistant TB and MDR-TB cases and MDR-TB treated cases. Not evaluated includes missing, unknown and transferred out. As treatment outcomes are reported at 12 months, treatment outcomes are only available to be reported on for cases notified in the previous year, at the time data are extracted for the report.

All drug sensitive TB cases reported to have died at last recorded treatment outcome, Wales, 2006–2015 Excludes initial and amplified to rifampicin resistant TB and MDR-TB treated cases