Visual deprivation in adults reverses two molecular correlates of cortical maturation. Visual deprivation in adults reverses two molecular correlates of.

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Visual deprivation in adults reverses two molecular correlates of cortical maturation. Visual deprivation in adults reverses two molecular correlates of cortical maturation. A, Top, Representative immunoblots for GABAAβ2/3 and GluR2 from juvenile and adult visual cortical homogenate. Bottom, Summary data demonstrate that visual deprivation induces a significant decrease in GABAAβ2/3 relative to GluR2 in juveniles and adults (*p < 0.05, unpaired t test). B, Top, Representative immunoblots for NR2b and NR2a from juvenile and adult visual cortical synaptoneurosomes. Bottom, Summary data demonstrate that visual deprivation induces a significant increase in NR2b relative to NR2a in juveniles and adults (*p < 0.01, unpaired t test). Data were normalized to age-matched LR for display. Error bars represent SEM. Hai-Yan He et al. J. Neurosci. 2006;26:2951-2955 ©2006 by Society for Neuroscience