The treatment of hypogonadism in men of reproductive age Edward D. Kim, M.D., Lindsey Crosnoe, B.S., Natan Bar-Chama, M.D., Mohit Khera, M.D., Larry I. Lipshultz, M.D. Fertility and Sterility Volume 99, Issue 3, Pages 718-724 (March 2013) DOI: 10.1016/j.fertnstert.2012.10.052 Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Clomiphene citrate (CC) works by blocking estrogen (E) at the pituitary. The pituitary sees less E, and makes more LH. More LH means that the Leydig cells in the testis make more T. (Adapted from Craig Neiderberger, M.D. http://urol.uic.edu/dept/niederberger.php and used with permission.) Fertility and Sterility 2013 99, 718-724DOI: (10.1016/j.fertnstert.2012.10.052) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions