Navigating the Deubiquitinating Proteome with a CompPASS

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Navigating the Deubiquitinating Proteome with a CompPASS Peter K. Jackson Cell Volume 138, Issue 2, Pages 222-224 (July 2009) DOI: 10.1016/j.cell.2009.07.008 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Identifying and Classifying High-Confidence Interacting Proteins Sowa et al. (2009) affinity purify from cultured human cells 75 deubiquitinating enzymes and identify their interacting proteins by mass spectrometric analysis. They further develop and use a method called CompPASS to analyze the mass spectrometry data to identify high-confidence interacting proteins and reveal potential biological implications for these interactions. Cell 2009 138, 222-224DOI: (10.1016/j.cell.2009.07.008) Copyright © 2009 Elsevier Inc. Terms and Conditions