Functional Insights of Plant GSK3-like Kinases: Multi-Taskers in Diverse Cellular Signal Transduction Pathways  Ji-Hyun Youn, Tae-Wuk Kim  Molecular Plant 

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Functional Insights of Plant GSK3-like Kinases: Multi-Taskers in Diverse Cellular Signal Transduction Pathways  Ji-Hyun Youn, Tae-Wuk Kim  Molecular Plant  Volume 8, Issue 4, Pages 552-565 (April 2015) DOI: 10.1016/j.molp.2014.12.006 Copyright © 2015 The Author Terms and Conditions

Figure 1 Classification and Phylogenetic Tree of Arabidopsis and Rice GSK3-like Kinases. (A) The GSK3-like kinase family of Arabidopsis thaliana and Oryza sativa is classified into four subgroups (I–IV). We propose to unify their official name as AtSKs (Arabidopsis thaliana Shaggy/GSK3-like kinases) or OsSKs (Oryza sativa Shaggy/GSK3-like kinases). (B) Phylogenetic analysis of Arabidopsis and rice GSK3-like kinases. Amino acid sequences of GSK3-like kinases, which were obtained from TAIR and TIGR resources, were aligned with ClustalW. The evolutionary history was inferred using the Maximum Parsimony method (Nei and Kumar, 2000). Evolutionary analyses were conducted in MEGA6 (Tamura et al., 2013). The scale bar indicates 10 amino acid substitutions. Molecular Plant 2015 8, 552-565DOI: (10.1016/j.molp.2014.12.006) Copyright © 2015 The Author Terms and Conditions

Figure 2 Signaling Network Mediated by GSK3-like Kinases in Arabidopsis and Rice. Arrows and bar ends indicate activation and inhibitory action, respectively, while dotted lines indicate hypothetical regulation. Substrates phosphorylated by GSK3-like kinases are marked with red circles containing the letter P. Molecular Plant 2015 8, 552-565DOI: (10.1016/j.molp.2014.12.006) Copyright © 2015 The Author Terms and Conditions