High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term.

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Presentation transcript:

High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long-term results from a prospective randomized trial from the Spanish cooperative group PETHEMA by Joan Bladé, Laura Rosiñol, Ana Sureda, Josep M. Ribera, Joaquín Díaz-Mediavilla, José García-Laraña, M. Victoria Mateos, Luis Palomera, Javier Fernández-Calvo, Josep M. Martí, Pilar Giraldo, Félix Carbonell, Manel Callís, Jesús Trujillo, Santiago Gardella, M. Jesús Moro, Abelardo Barez, Alfons Soler, Llorenç Font, Montserrat Fontanillas, and Jesús San Miguel Blood Volume 106(12):3755-3759 December 1, 2005 ©2005 by American Society of Hematology

PFS in patients given HDT intensification compared with those who were continued on conventional dose chemotherapy. PFS in patients given HDT intensification compared with those who were continued on conventional dose chemotherapy. Chemo indicates chemotherapy; auto, autologous transplantation. Joan Bladé et al. Blood 2005;106:3755-3759 ©2005 by American Society of Hematology

OS of patients undergoing HDT intensification compared with those who were continued on conventional dose chemotherapy. OS of patients undergoing HDT intensification compared with those who were continued on conventional dose chemotherapy. Chemo indicates chemotherapy; auto, autologous transplantation. Joan Bladé et al. Blood 2005;106:3755-3759 ©2005 by American Society of Hematology

Survival after relapse in patients undergoing HDT compared with survival in those given standard dose chemotherapy. Survival after relapse in patients undergoing HDT compared with survival in those given standard dose chemotherapy. Chemo indicates chemotherapy; auto, autologous transplantation. Joan Bladé et al. Blood 2005;106:3755-3759 ©2005 by American Society of Hematology