Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy Damien Leger, MD, Moshe Laudon,

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Presentation transcript:

Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy Damien Leger, MD, Moshe Laudon, PhD, Nava Zisapel, PhD The American Journal of Medicine Volume 116, Issue 2, Pages 91-95 (January 2004) DOI: 10.1016/j.amjmed.2003.07.017

Figure Frequency distribution of nocturnal 6-sulfatoxymelatonin excretion in healthy volunteers (n = 30 [open squares], ages 20 to 35 years; n = 29 [open circles], ages ≥55 years) and in patients with insomnia aged ≥55 years (n = 517 [closed circles]). The American Journal of Medicine 2004 116, 91-95DOI: (10.1016/j.amjmed.2003.07.017)