A, P276-00 causes G2-M arrest with apoptosis in asynchronous population of PC-3 when exposed to 1.5 and 5 μmol/L P276-00 for various time points. A, P276-00.

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Presentation transcript:

A, P276-00 causes G2-M arrest with apoptosis in asynchronous population of PC-3 when exposed to 1.5 and 5 μmol/L P276-00 for various time points. A, P276-00 causes G2-M arrest with apoptosis in asynchronous population of PC-3 when exposed to 1.5 and 5 μmol/L P276-00 for various time points. The DNA histograms were generated by flow cytometry and the percentage of cells in each phase of the cell cycle was determined using ModFit analysis. B, P276-00 causes significant apoptosis in asynchronous population of HL-60 cells from 6 h onwards when treated with concentrations of 1.5 and 5 μmol/L P276-00 for various time points. Kalpana S. Joshi et al. Mol Cancer Ther 2007;6:926-934 ©2007 by American Association for Cancer Research