Kaplan-Meier survival analysis of p53 mutation in the overall breast tumor series. Kaplan-Meier survival analysis of p53 mutation in the overall breast.

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Kaplan-Meier survival analysis of p53 mutation in the overall breast tumor series. Kaplan-Meier survival analysis of p53 mutation in the overall breast tumor series. A, survival of breast cancer patients with wild-type p53 (black line) compared with those with mutant p53 (blue line; P < 0.0001). B, survival of patients with wild-type p53 (black line) compared with those with DNA contact p53 mutations (red line; P = 0.5692) or with denaturing p53 mutations (blue line; P = 0.0010). C, survival of patients with wild-type p53 (black line) compared with those with p53 mutations in the L2/L3 domain (red line; P = 0.0037) or with p53 mutations lying outside this domain (blue line; P < 0.0001). Brenda Powell et al. Clin Cancer Res 2000;6:443-451 ©2000 by American Association for Cancer Research