ESKM treatment does not affect leukocyte or HSC counts in HLA-A

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ESKM treatment does not affect leukocyte or HSC counts in HLA-A ESKM treatment does not affect leukocyte or HSC counts in HLA-A*02:01+ transgenic mice. ESKM treatment does not affect leukocyte or HSC counts in HLA-A*02:01+ transgenic mice. Animals (n = 5 per group) were treated with 100 μg ESKM or hIgG1 isotype control on days 0 and 4; blood and bone marrow were harvested on day 5. Data points are averages of each group, and error bars represent SEM. A, total white blood cell (WBC) and WBC subset cell counts. B, absolute number and frequency of lineage− SCA1+ KIT+ (LSK) cells. C, absolute number and frequency of long-term HSCs (Slamf1+ CD34− LSK cells). Nicholas Veomett et al. Clin Cancer Res 2014;20:4036-4046 ©2014 by American Association for Cancer Research