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Stephen H. Little JIMG 2012;5:677-680 Cautious Quantification of the Double Jet Three-dimensional color Doppler clearly identifies 2 distinct regurgitant jets in a patient with functional mitral regurgitation (upper left). The vena contracta area (VCA) for each mitral regurgitation (MR) jet is identified by manual planimetry (upper right). Tissue gain setting can influence the size of the visible VC area (bottom panels). Compared with a mid-range tissue gain setting (∼50%), a low tissue gain setting (20%) creates a larger total VCA, whereas a high tissue gain setting (80%) creates a smaller total VCA. Stephen H. Little JIMG 2012;5:677-680 American College of Cardiology Foundation