Investigation on the role of necroptosis in alopecia areata: A preliminary study Yong Hyun Jang, MD, PhD, Meiling Jin, MD, Sun Young Moon, MD, Dong Hyuk.

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Investigation on the role of necroptosis in alopecia areata: A preliminary study Yong Hyun Jang, MD, PhD, Meiling Jin, MD, Sun Young Moon, MD, Dong Hyuk Eun, MD, Weon Ju Lee, MD, PhD, Seok-Jong Lee, MD, PhD, Moon Kyu Kim, MD, PhD, Sang-Hyun Kim, PhD, Do Won Kim, MD, PhD Journal of the American Academy of Dermatology Volume 75, Issue 2, Pages 436-439 (August 2016) DOI: 10.1016/j.jaad.2016.03.015 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Messenger RNA (mRNA) expression of receptor interacting protein kinase (RIPK)3 (A), RIPK1 (B), and mixed lineage kinase domain-like (MLKL) protein (C) in the lesional skin of patients with alopecia areata (AA) showed no statistically significant differences compared with that of healthy control subjects. D, There was also no significant difference of caspase-8 mRNA expression. Journal of the American Academy of Dermatology 2016 75, 436-439DOI: (10.1016/j.jaad.2016.03.015) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 The protein expressions of receptor interacting protein kinase (RIPK)3 (A) and RIPK1 (B) were not up-regulated in the lesional skin of patients with alopecia areata (AA). Journal of the American Academy of Dermatology 2016 75, 436-439DOI: (10.1016/j.jaad.2016.03.015) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions