A New Window onto Translational Repression by Bacterial sRNAs

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A New Window onto Translational Repression by Bacterial sRNAs Jamie Richards, Joel G. Belasco Molecular Cell Volume 32, Issue 6, Pages 751-753 (December 2008) DOI: 10.1016/j.molcel.2008.12.009 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 Translational Repression by Bacterial sRNAs (A) Ribosome binding in the absence of an sRNA. The 30S and 50S ribosomal subunits (blue ovoids) bind to an mRNA segment comprising portions of the 5′ untranslated region (black line) and coding region (amber cylinder), including the SD (AGGA) and the start codon (AUG). (B) Inhibition of ribosome binding by an sRNA (bent black line) base paired to the SD. (C) Inhibition of ribosome binding by an sRNA base paired downstream of the start codon and within the five codon window. Molecular Cell 2008 32, 751-753DOI: (10.1016/j.molcel.2008.12.009) Copyright © 2008 Elsevier Inc. Terms and Conditions