The lifetime prevalence of abdominal aortic aneurysms among siblings of aneurysm patients is eightfold higher than among siblings of spouses: An analysis.

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The lifetime prevalence of abdominal aortic aneurysms among siblings of aneurysm patients is eightfold higher than among siblings of spouses: An analysis of 187 aneurysm families in Nova Scotia, Canada  Toru Ogata, MD, Gerald L. MacKean, MD, C. William Cole, MD, Claudette Arthur, BN, MBA, Pantelis Andreou, PhD, Gerard Tromp, PhD, Helena Kuivaniemi, MD, PhD  Journal of Vascular Surgery  Volume 42, Issue 5, Pages 891-897 (November 2005) DOI: 10.1016/j.jvs.2005.08.002 Copyright © 2005 The Society for Vascular Surgery Terms and Conditions

Outline of the Nova Scotia AAA study Outline of the Nova Scotia AAA study. The objective of the study was to determine the prevalence of AAA among the first-degree relatives of known AAA patients (referred here as “AAA probands”) in a well-characterized population in Nova Scotia, Canada. Secondly, we examined two comparison groups, the spouses of the AAA probands, and the first-degree relatives of the spouses with the assumption that they shared similar environmental exposures and cultural habits. In the present study we report the findings on the comparison between the two sibling groups, the siblings of the AAA probands and the siblings of the spouses. The spouse group is smaller than the proband group, because143 AAA probands had no spouses. US, ultrasonography; AAA, abdominal aortic aneurysm. *(number of individuals; %) Journal of Vascular Surgery 2005 42, 891-897DOI: (10.1016/j.jvs.2005.08.002) Copyright © 2005 The Society for Vascular Surgery Terms and Conditions