General scheme of the events triggered by C

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Nat. Rev. Neurol. doi: /nrneurol

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General scheme of the events triggered by C General scheme of the events triggered by C. perfringens alpha-toxin during gas gangrene. General scheme of the events triggered by C. perfringens alpha-toxin during gas gangrene. The pleiotropic effects of C. perfringens alpha-toxin in diverse cell types contribute to reducing vascular perfusion and causing tissue damage, which enhance the conditions for bacterial growth and lead to shock and multiple organ failure. Marietta Flores-Díaz et al. Microbiol. Mol. Biol. Rev. 2016; doi:10.1128/MMBR.00082-15