SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression. SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression.

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Presentation transcript:

SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression. SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression. Serum-starved SBC-5 cell lines (SBC-5 miR-335+, SBC-5 miR-29a+, and SBC-5 VectorCtrl) and SBC-3 cells were lysed in RIPA buffer, and IGF-IR expression was studied by Western blotting. Compared with SBC-5 VectorCtrl, IGF-IR expression was lower in SBC-5 miR-335+ and SBC-3 cells, and did not show difference between SBC-5 VectorCtrl and SBC-5 miR-29a+. Meng Gong et al. Mol Cancer Res 2014;12:101-110 ©2014 by American Association for Cancer Research