Influenza vaccine enhances NK cell function through IFN-α.

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Presentation transcript:

Influenza vaccine enhances NK cell function through IFN-α. Influenza vaccine enhances NK cell function through IFN-α. A, time course quantification of serum cytokine levels in control B6 mice following influenza vaccine administration. B, ability of NK cells to kill tumor targets from (left) IFNAR-KO and B6 mice post-influenza vaccine and (right) from indicated treatment groups. Quantification of B16lacZ lung tumor metastases in (C) B6 and (D) IFNAR-KO mice following indicated perioperative treatment. n = 4–5 per group. **, P > 0.005; ***, P = 0.0001; n.s., not significant. Data are representative of 3 experiments. Lee-Hwa Tai et al. Clin Cancer Res 2013;19:5104-5115 ©2013 by American Association for Cancer Research