Monitoring level of sedation with bispectral EEG analysis: comparison between hypothermic and normothermic cardiopulmonary bypass† D. Schmidlin, P. Hager,

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Presentation transcript:

Monitoring level of sedation with bispectral EEG analysis: comparison between hypothermic and normothermic cardiopulmonary bypass† D. Schmidlin, P. Hager, E.R. Schmid British Journal of Anaesthesia Volume 86, Issue 6, Pages 769-776 (June 2001) DOI: 10.1093/bja/86.6.769 Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 1 Processed EEG parameters (BIS, SEF 95). Open symbols represent the hypothermic CPB group, hatched symbols the normothermic CPB group. Significant changes over time are indicated by *, **, and ¶, as described below. Values of the box plots are expressed as median, 10th, 25th, 75th, and 90th percentile. Isolated values are depicted as circles. (a) BIS (bispectral analysis). *Day before surgery vs before induction of anaesthesia; P=0.0003. **Before induction vs after induction of anaesthesia; P<0.0003. ¶End of surgery vs clinical awakening; (P<0.0003). (b) SEF 95 (spectral edge frequency at 95% level). *Day before surgery vs before induction of anaesthesia; P=0.049. **Before induction vs after induction of anaesthesia; P=0.0024. ¶End of surgery vs clinical awakening; P=0.0018. British Journal of Anaesthesia 2001 86, 769-776DOI: (10.1093/bja/86.6.769) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 2 BIS and temperature during CPB. Open symbols represent the hypothermic CPB group, hatched symbols the normothermic CPB group. Values of the box plots are expressed as median, 10th, 25th, 75th, and 90th percentile. Isolated values are depicted as circles. (a) BIS during CPB. Values between groups were significantly different; P=0.001. (b) Blood temperature during CPB. Values between groups were significantly different; P<0.0001. (c) BIS values divided by blood temperature. There was no difference over time and no difference between the hypothermic and normothermic CPB groups. British Journal of Anaesthesia 2001 86, 769-776DOI: (10.1093/bja/86.6.769) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions