Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang  Cell Stem Cell 

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Where PI3K/Akt Meets Smads: The Crosstalk Determines Human Embryonic Stem Cell Fate  Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang  Cell Stem Cell  Volume 10, Issue 3, Pages 231-232 (March 2012) DOI: 10.1016/j.stem.2012.02.008 Copyright © 2012 Elsevier Inc. Terms and Conditions

Figure 1 Heregulin and IGF-1 via PI3K/Akt and Activin via Smad2/3 Cooperate to Maintain Self-Renewal of hESCs Red indicates the activated state of signaling molecules, whereas blue indicates the repressive state. The dashed line indicates the regulation with unclear mechanisms. Cell Stem Cell 2012 10, 231-232DOI: (10.1016/j.stem.2012.02.008) Copyright © 2012 Elsevier Inc. Terms and Conditions

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