Intra-device comparison of albuterol captured at the end of the endotracheal tube (lung dose). Intra-device comparison of albuterol captured at the end.

Slides:



Advertisements
Similar presentations
Effect of nasal positive expiratory pressure (PEP) on 6-min walk test (6MWT) distance and pre- to post-exercise increase in lung volumes in each individual.
Advertisements

Effect of gas density on aerosol delivery from a pressurized metered-dose inhaler (pMDI) and jet nebulizer. A. Albuterol was administered via a pMDI and.
Placement of Aeroneb with HFOV
Aerosol Therapy & HFNC Natalie Napolitano, MPH, RRT-NPS, FAARC
The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.
Airway pressure and flow waveforms during constant flow volume control ventilation, illustrating the effect of an end-inspiratory breath-hold. Airway pressure.
Propagation of pneumonia and lung injury.
AEROSOL DELIVERY THROUGH ADULT HIGH FLOW NASAL CANNULA:
Chapter 3 Administration of Aerosolized Agents
Trigger pressure-time product (PTP) with zero pressure support, with no leak, medium leak, and large leak. Trigger pressure-time product (PTP) with zero.
Relationship between the recruited volume and the arithmetic mean of the ratios of lung density at PEEP 15 cm H2O to lung density at PEEP 5 cm H2O (μP15/P5)
Air flow during ventilator-supported speech production.
The Spectrum mask incorporates the leak port into the circuit, whereas the Mirage mask incorporates the leak port into the mask. The Spectrum mask incorporates.
The Arndt endobronchial blocker, one of the commercially available endobronchial blockers for lung isolation. The Arndt endobronchial blocker, one of the.
Picture of bubble PEP devices.
Respirable mass, expressed as percent of nominal dose.
Schematic representation of vertical pleural pressure (Ppl) distribution from the apex to the bases in the upright position and their respective diminishment.
Cuff-pressure changes after the addition of 5 mL and 10 mL of air into the cuff of 3 artificial airways, after initial baseline of 30 cm H2O established.
Even though this patient is undergoing positive-pressure mechanical ventilation, the first 4 breaths have a relatively negative pressure (ie, pressure.
Noninvasive ventilation-neurally adjusted ventilatory assist (NIV-NAVA) where each patient effort is captured but support is insufficient (maximum electrical.
An example of delayed cycling during pressure-support ventilation of a patient with COPD, on a Puritan Bennett 7200 ventilator, which has a flow-termination.
The third breath has a negative deflection (ie, below PEEP) at the end of the mechanical breath (arrow A) associated with a flow increase (arrow B), indicating.
The peak flows (60 L/min) and flow patterns are the same for all the breaths. The peak flows (60 L/min) and flow patterns are the same for all the breaths.
Two methacholine dosing schemes.
Comparison of airway pressure release ventilation (APRV) (blue curve) and biphasic positive airway pressure (BIPAP) (black curve). Comparison of airway.
Trigger and synchronization windows.
In this tracing of 30 seconds, 4 breaths are ineffectively triggered (arrows IT) and 7 are effectively triggered. In this tracing of 30 seconds, 4 breaths.
This tracing depicts 30 seconds of information.
A: Axial chest computed tomogram (CT) image with lung-window setting reveals overdistention of the endotracheal tube (arrow head) and a large defect of.
Work rate as a function of pressurization rate and cycling-off threshold, during pressure-support ventilation of (A) patients with acute lung injury (ALI),
Example of Aerogen Solo Nebulizer before use with a fill volume of 3 mL normal saline (arrow 1) (A); the same nebulizer after random premature cessation.
Schematic drawing of alveolar sizes at upper (A), middle (B), and lower dependent (C) lung regions at end expiration and end inspiration. Schematic drawing.
Effect of respiratory mechanics on cycling of pressure support from inhalation to exhalation. Effect of respiratory mechanics on cycling of pressure support.
Carbon monoxide (CO) delivery system used in animal models and Phase 1 clinical trials. Carbon monoxide (CO) delivery system used in animal models and.
Gap size differences between the fiberoptic bronchoscope and a standard endotracheal tube (ETT) are shown. Gap size differences between the fiberoptic.
Comparison of alkaline glycine to normal saline inhalation (study 1).
Assembly used to convert a standard ventilator to an intermittent mandatory ventilation circuit. Assembly used to convert a standard ventilator to an intermittent.
Blind intubation through a supraglottic airway device (SAD), in this case, the laryngeal mask airway (LMA) Fastrach. Blind intubation through a supraglottic.
Breathing frequency and PaCO2: comparison between high-flow nasal cannula oxygen therapy (HFNC) and comparative therapies in 8 studies. Breathing frequency.
Screen shot of test acceptability and reproducibility for spirometry (upper panel) and diffusion capacity of the lung for carbon monoxide (DLCO) (lower.
A: Changes in percent of predicted following bronchodilator for spirometric and lung volumes variables. A: Changes in percent of predicted following bronchodilator.
Alveolar dead space. Alveolar dead space. A: An ideal unit (top) receives nearly equal amounts of ventilation and perfusion. B: When perfusion drops (and.
Inter-device comparison
A novel multi-channeled neonatal patient Y-piece device (AFECTAIR) developed as part of an aerosolized lung surfactant administration system to be used.
Negative pressures generated in our airway model.
A: Pressure ulcer on the left cheek of a patient after 1 week of prone positioning using a commercially available endotracheal tube (ETT) holder. A: Pressure.
Kaplan-Meier curve for the probability of noninvasive ventilation (NIV) failure relative to continuous use of NIV and stratified for Acute Physiology and.
Total drug dose by device and condition while delivering 1 mL of ribavirin (5 min for the small-particle aerosol generator [SPAG] or 2 min for the vibrating.
Experimental setup of particle distribution using the 8-stage Andersen cascade impactor and in vitro module using an absolute filter. Experimental setup.
Graphical representation of the locations where spontaneous breaths may occur during the airway pressure (Paw) release ventilation ventilatory cycle. Graphical.
Flow, airway pressure, and transversus abdominis electromyogram (EMG) waveforms from a mechanically ventilated patient with COPD receiving pressure-support.
Schematic of mechanisms behind the better recruitment of alveoli with spontaneous breathing. Schematic of mechanisms behind the better recruitment of alveoli.
Plots of alveolar PO2, hemoglobin saturation, and alveolar PCO2 as a function of alveolar ventilation in a normal subject at sea level (inspired oxygen.
Components of a patient-triggered mechanical breath.
FEV1 and FVC for the control group (without noninvasive ventilation [NIV]), NIV with an inspiratory pressure (IPAP) of 15 cm H2O and expiratory pressure.
The CoPilot. The CoPilot. Like the GlideScope, this video laryngoscope has an angulated blade to facilitate clear image capture of the glottic opening.
Tidal volume (VT) error (% difference between set and actual values) was determined for each ventilator at VT of 300, 500, and 700 mL. Tidal volume (VT)
A: Work of breathing before and after nebulized terbutaline delivered via standard nebulization method versus delivered during continuous positive airway.
The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.
Double lumen endotracheal tube (DLET) with its upper channel dedicated to fiberoptic bronchoscopy (FOB) and lower channel exclusively dedicated to ventilation.
Experimental setup. Experimental setup. Each tested ventilator was connected to the TTL test lung via a ventilator circuit. An oxygen analyzer, a pressure.
For inspiratory load compensation testing, this threshold positive expiratory pressure (PEP) training device was inverted and connected to a respiratory.
Delivery efficiency with different devices, ventilator positions, and ventilator settings. Delivery efficiency with different devices, ventilator positions,
A: Comparison of pediatric lung transplant survival between different age groups. A: Comparison of pediatric lung transplant survival between different.
Average drug doses in the peripheral lung, central lung, and extrathoracic airway; residual drug left in the device; and residual drug that was exhaled.
Percent of extremely-low-birth-weight (ELBW) babies alive and off mechanical ventilation at 7 days, and median days on mechanical ventilation for ELBW.
Mean ± SD PEEP requirements from randomized clinical trials of lung-protective ventilation whereby PEEP and FIO2 were titrated to maintain PaO2
Setup of the BiPAP Synchrony with an inspiratory filter and single-limb passive circuit, with the filter placed over the fixed leak to collect aerosol.
Effects of an automated endotracheal-tube-compensation system on a pressure-support breath. Effects of an automated endotracheal-tube-compensation system.
Presentation transcript:

Intra-device comparison of albuterol captured at the end of the endotracheal tube (lung dose). Intra-device comparison of albuterol captured at the end of the endotracheal tube (lung dose). With the Updraft II Opti-Neb jet nebulizer, lung dose with the 2.5 mg/3 mL solution when placed at the Y-piece was lower than all, and lung dose with the 5.0 mg/3.5 mL and 7.5 mg/4 mL solutions when positioned at the ventilator was similar to humidifier and was greater than at the Y-piece and 30 cm from the Y-piece. With the Salter 8900 jet nebulizer, lung dose with the 2.5 mg/3 mL solution when placed at the humidifier was greater than all other positions, and lung dose with the 5.0 mg/3.5 mL and 7.5 mg/4 mL solutions when positioned at the ventilator was similar to humidifier and was greater than Y-piece and 30 cm from the Y-piece. With the Maquet ultrasonic nebulizer, lung dose with the 2.5 mg/3 mL solution when placed at the humidifier was greater than all other positions, and also lung dose was greater at the ventilator than at the Y-piece; output with the 5.0 mg/3.5 mL solution when placed at the humidifier was greater than the Y-piece and 30 cm from the Y-piece and lung dose was greater at the ventilator than at the Y-piece; lung dose with the 7.5 mg/4 mL solution when placed at the humidifier was greater than all other positions, and lung dose was greater at the ventilator than at the Y-piece and 30 cm from the Y-piece. With the Aerogen Solo vibrating mesh nebulizer, lung dose with all solutions tested when positioned at the ventilator was similar to humidifier and was greater than Y-piece and 30 cm from the Y-piece. Ariel Berlinski, and J Randy Willis Respir Care 2013;58:1124-1133 (c) 2012 by Daedalus Enterprises, Inc.