Relationship between organ failure and mortality in acute-on-chronic liver failure (ACLF). Relationship between organ failure and mortality in acute-on-chronic.

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Relationship between organ failure and mortality in acute-on-chronic liver failure (ACLF). Relationship between organ failure and mortality in acute-on-chronic liver failure (ACLF). Twenty-eight-day mortality rates of patients with decompensated cirrhosis with (red bars) and without (green bars) ACLF according to the diagnostic criteria proposed in the CANONIC study.9 Patients are divided into the following categories: patients with no organ failure (OF); patients with a single non-kidney organ failure without kidney dysfunction (KD; a serum creatinine level of 1.5–1.9 mg/dL) or brain dysfunction (BD; grade 1–2 hepatic encephalopathy); patients with a single kidney failure; patients with a single non-kidney organ failure with KD and/or BD; patients with two organ failures and patients with three or more organ failures. Adapted with permission from Arroyo et al.27 Ruben Hernaez et al. Gut 2017;66:541-553 Copyright © BMJ Publishing Group Ltd & British Society of Gastroenterology. All rights reserved.