SCF-Mediated Proteolysis and Negative Regulation in Ethylene Signaling Stefan Kepinski, Ottoline Leyser  Cell  Volume 115, Issue 6, Pages 647-648 (December 2003) DOI: 10.1016/S0092-8674(03)00978-4

Figure 1 The Basics of Ethylene Signaling Ethylene acts through a series of both positive and negative regulators to influence gene expression. Ethylene inactivates the ETR/ERS family of ethylene receptors, releasing the repression of downstream components which contribute to the accumulation of the transcription factor EIN3 (see text). In the absence of ethylene, EIN3 is constitutively degraded via a novel component, SCFEBF1/2 . Cell 2003 115, 647-648DOI: (10.1016/S0092-8674(03)00978-4)