Treatment decision trends in the infertility patient journey from 78,958 cycles in a real- world database: impact of age, diagnosis, and year of treatment 

Slides:



Advertisements
Similar presentations
Oocyte number as a predictor for ovarian hyperstimulation syndrome and live birth: an analysis of 256,381 in vitro fertilization cycles  Ryan G. Steward,
Advertisements

Andrew J. Krentz, M.D., Elizabeth Barrett-Connor, M.D. 
Yuqian Cui, M. D. , Ph. D. , Yuhua Shi, M. D. , Ph. D. , Linlin Cui, M
Hatem Abu Hashim  Reproductive BioMedicine Online 
Age at menarche: a predictor of diminished ovarian function?
Increased prevalence of anxiety symptoms in women with polycystic ovary syndrome: systematic review and meta-analysis  Anuja Dokras, M.D., Ph.D., Shari.
Fertility and Sterility  Volume 97, Issue 3, Pages (March 2012)
Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women  Babak Mokhlesi, M.D.,
Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome 
Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) in IVF patients with polycystic ovary syndrome: correlations with outcome 
Follicular-phase ovarian follicular fluid and plasma cytokine profiling of natural cycle in vitro fertilization patients  N. Ellissa Baskind, M.B.Ch.B.,
Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study  Angela Kerchner, B.A., Whitney Lester,
Fertility and Sterility  Volume 89, Issue 3, Pages (March 2008)
Temporal trends in clomiphene citrate use: a population-based study
Is the addition of metformin efficacious in the treatment of clomiphene citrate-resistant patients with polycystic ovary syndrome? A structured literature.
Changes in affect and state anxiety across an in vitro fertilization/intracytoplasmic sperm injection cycle  Neha N. Mahajan, Ph.D., Deborah A. Turnbull,
The impact of total gonadotropin dose on spontaneous abortion rates and early pregnancy outcomes in infertile couples undergoing gonadotropin induction/intrauterine.
The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.
Biomarkers of ovarian response: current and future applications
Modified natural cycle in in vitro fertilization
Grant D.E. McWilliams, D.O., John L. Frattarelli, M.D. 
How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization  Robert L. Klitzman, M.D.  Fertility.
FSH receptor, KL1/2, P450, and PAPP genes in granulosa-lutein cells from in vitro fertilization patients show a different expression pattern depending.
The role of steroid hormone supplementation in non–assisted reproductive technology treatments for unexplained infertility  Alexander M. Quaas, M.D.,
Selection of patients for natural cycle in vitro fertilization combined with in vitro maturation of immature oocytes  Jin-Ho Lim, M.D., Seong-Ho Yang,
Improved monofollicular ovulation in anovulatory or oligo-ovulatory women after a low- dose step-up protocol with weekly increments of 25 international.
Effect of N-acetyl-cysteine after ovarian drilling in clomiphene citrate-resistant PCOS women: a pilot study  A. Nasr  Reproductive BioMedicine Online 
Low fertility awareness in United States reproductive-aged women and medical trainees: creation and validation of the Fertility & Infertility Treatment.
Letrozole versus combined metformin and clomiphene citrate for ovulation induction in clomiphene-resistant women with polycystic ovary syndrome: a randomized.
Epidemiology and Adverse Cardiovascular Disease (CVD) Risk Profile of Polycystic Ovarian Syndrome (PCOS): The Kaiser Permanente Polycystic Ovarian Syndrome.
Cumulative live-birth rates per total number of embryos needed to reach newborn in consecutive in vitro fertilization (IVF) cycles: a new approach to.
Does metformin affect the ovarian response to gonadotropins for in vitro fertilization treatment in patients with polycystic ovary syndrome and reduced.
Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): modifying the CONSORT statement    Fertility and Sterility  Volume 102,
Poor Laboratory Air Quality and Its Impact on Early Embryo Development
Hyperglycemia Stimulates Activation of Nuclear Factor κB (NFκB) in Mononuclear Cells (MNC) of Women With Polycystic Ovary Syndrome (PCOS)  F. Gonzalez,
Patients with severe ovarian hyperstimulation syndrome can be managed safely with aggressive outpatient transvaginal paracentesis  Laura P. Smith, M.D.,
Fertility and Sterility
Ovulation induction in women with polycystic ovary syndrome
Venous thromboembolism in relation to in vitro fertilization: an approach to determining the incidence and increase in risk in successful cycles  Karin.
Tiffany D. Justice, M.D., Steven T. Nakajima, M.D. 
Treatment of Ovarian Hyperstimulation Syndrome Utilizing a Dopamine Agonist and Gonadotropin Releasing Hormone antagonist  N. Rollene, M. Amols, S. Hudson,
Evaluation of diagnostic testis biopsy and the repetition of testicular sperm extraction surgeries in infertility patients  Alayman Hussein, M.B.B.C.H.,
Birth outcomes after spontaneous or assisted conception among infertile Australian women aged 28 to 36 years: a prospective, population-based study  Danielle.
Increased secretion of amylin in women with polycystic ovary syndrome
Fertility and Sterility
Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation.
In vitro fertilization and breast cancer: is there cause for concern?
Banu Ucar, M. D. , Volkan Noyan, M. D. , Osman Caglayan, M. D
Complex chromosome abnormality in patients with in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI)  S.P. Weng, T.C.J. Wu, S.P. Kang,
Effects of metformin on body mass index, menstrual cyclicity, and ovulation induction in women with polycystic ovary syndrome  Derek A Haas, M.D., Bruce.
Impact of laparoscopic ovarian drilling on anti-Müllerian hormone levels and ovarian stromal blood flow using three-dimensional power Doppler in women.
Pregnancy outcome in infertile patients with polycystic ovary syndrome who were treated with metformin  Samuel S. Thatcher, M.D., Ph.D., Elizabeth M.
Stephanie A. Beall, M.D., Ph.D., Alan DeCherney, M.D. 
P. Callum, L. Isley  Fertility and Sterility 
Paolo Moghetti, M.D.  Fertility and Sterility 
Moderately elevated levels of basal follicle-stimulating hormone in young patients predict low ovarian response, but should not be used to disqualify.
Are patients with idiopathic hirsutism (IH) insulin resistant
Comparison of clomiphene citrate, metformin, or the combination of both for first-line ovulation induction and achievement of pregnancy in 154 women with.
Increased total and phosphorylated glycogen synthase kinase-3 (GSK-3) in the adipocytes of patients with the polycystic ovary syndrome (PCOS)  W.Y. Chang,
Impact of luteinizing hormone administration on gonadotropin-releasing hormone antagonist cycles: an age-adjusted analysis  Ernesto Bosch, M.D., Elena.
Proteomic biomarkers for ovarian cancer risk in women with polycystic ovary syndrome: a systematic review and biomarker database integration  Nicolas.
High singleton live birth rate confirmed after ovulation induction in women with anovulatory polycystic ovary syndrome: validation of a prediction model.
David H. Barad, M.D., M.S., Norbert Gleicher, M.D. 
Comparison of the Ovulation Induction and Hormone Profile Between Anastrozole and Clomiphene Citrate in Women With Infertility  H. Wu, P. Chen, N.M. Wang,
Egg production predicts a doubling of in vitro fertilization pregnancy rates even within defined age and ovarian reserve categories  Melissa C. Yih, M.D.,
Defining the proliferative phase endometrial defect
Performance of basal follicle-stimulating hormone and patient's age in the prediction of poor ovarian response and IVF outcome of women who developed.
Increased risk of depressive disorders in women with polycystic ovary syndrome  Elizabeth Hollinrake, B.S., Alison Abreu, M.D., Michelle Maifeld, R.N.C.,
Conversion from assisted reproductive technology to intrauterine insemination in low responders: Is it advantageous?  John M. Norian, M.D., Eric D. Levens,
The cumulative probability of liveborn multiples after in vitro fertilization: a cohort study of more than 10,000 women  Beth A. Malizia, M.D., Laura.
Presentation transcript:

Treatment decision trends in the infertility patient journey from 78,958 cycles in a real- world database: impact of age, diagnosis, and year of treatment  G.L. Mottla, K.S. Richter, B. Kaplan, B. Hayward, M.C. Mahony  Fertility and Sterility  Volume 107, Issue 3, (March 2017) DOI: 10.1016/j.fertnstert.2017.02.078 Copyright © 2017 Terms and Conditions

Figure 1 Treatment Pattern by (A) Primary Diagnosis (All Age Groups), (B) Age (All Diagnosis Groups), and (C) Year (All Age and Diagnosis Groups). OI, ovulation induction; IVF, in vitro fertilization; PCOS, polycystic ovarian syndrome. Fertility and Sterility 2017 107, DOI: (10.1016/j.fertnstert.2017.02.078) Copyright © 2017 Terms and Conditions