Coexpression of other immune genes with ImSig core signatures.

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Coexpression of other immune genes with ImSig core signatures. Coexpression of other immune genes with ImSig core signatures. A, Correlation network of genes associated with the immune clusters during trachomatis infection. ImSig genes are colored according to the different immune cell types they represent, whereas the genes coclustering with the ImSig immune genes are shown as nodes without color and reduced in size. Highlighted with a greater node size and label are a few well-known immune-modulatory genes present in the immediate vicinity of the signature genes. B, Bar plots of the average expression intensity of a few well-known immune-modulatory genes across the three patient groups. Ajit J. Nirmal et al. Cancer Immunol Res 2018;6:1388-1400 ©2018 by American Association for Cancer Research