Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood  Adnan Custovic, MD, PhD, Lars Soderstrom, MSc, Staffan Ahlstedt, PhD, Peter D. Sly, MD, PhD, Angela Simpson, MD, PhD, Patrick G. Holt, PhD  Journal of Allergy and Clinical Immunology  Volume 127, Issue 6, Pages 1480-1485 (June 2011) DOI: 10.1016/j.jaci.2011.03.014 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Cat allergen–specific IgE and rFel d 1–specific IgG and IgG4 antibody levels among children with and without current wheeze in the UK and Australian cohorts. Journal of Allergy and Clinical Immunology 2011 127, 1480-1485DOI: (10.1016/j.jaci.2011.03.014) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Excellent correlation between IgE antibodies of whole-allergen extract for cat and IgE antibodies to rFel d 1. Journal of Allergy and Clinical Immunology 2011 127, 1480-1485DOI: (10.1016/j.jaci.2011.03.014) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 A and B, Fitted predicted probability for current wheeze at a given cat-specific IgE value and rFel d 1–specific IgG value derived from the multivariate logistic regression analysis for children in the UK (Fig 3, A) and Australia (Fig 3, B). C and D, Fitted predicted probability for current wheeze at a given cat-specific IgE value and rFel d 1–specific IgG4 value derived from the multivariate logistic regression analysis for children in the UK (Fig 3, C) and Australia (Fig 3, D). Journal of Allergy and Clinical Immunology 2011 127, 1480-1485DOI: (10.1016/j.jaci.2011.03.014) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions