Representative photograph of somatic mutations detected by PCR-SSCP.

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Representative photograph of somatic mutations detected by PCR-SSCP. Representative photograph of somatic mutations detected by PCR-SSCP. All OC samples with the aberrant bands that appeared different from wild-type pattern in the SSCP gel were subject to confirmation. Both tumor (T) and adjacent normal (N) tissues were confirmed independently for the shifts. Arrows, shifted bands that are present only in tumor lanes but absent in corresponding normal lanes. Note the weak shifted band in one normal sample of OC18 in addition to the strong shift in the tumor lane. Taiping Chen et al. Cancer Res 2001;61:4679-4682 ©2001 by American Association for Cancer Research