WP1066 inhibits the progression of OCIM2 cells through the cell cycle.

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WP1066 inhibits the progression of OCIM2 cells through the cell cycle. WP1066 inhibits the progression of OCIM2 cells through the cell cycle. Depicted are the histograms and percentages of cells in the G0-G1, S, and G2-M phases of the cell cycle after 2 to 14 h of incubation with 2 μmol/L WP1066. A higher percentage of OCIM2 cells in the G0-G1 phase was detected in the WP1066-treated cells when compared with the control (WP1066-untreated) cells, 72.4% versus 51.4%, after 14 h of incubation. Alessandra Ferrajoli et al. Cancer Res 2007;67:11291-11299 ©2007 by American Association for Cancer Research