Thomas M. Egan, MDa (by invitation), Frank C

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Presentation transcript:

Improved results of lung transplantation for patients with cystic fibrosis Thomas M. Egan, MDa (by invitation), Frank C. Detterbeck, MDa (by invitation), Michael R. Mill, MDa (by invitation), Linda J. Paradowski, MDb (by invitation), Rudy P. Lackner, MDa (by invitation), W.David Ogden, MDa (by invitation), James R. Yankaskas, MDb (by invitation), Jan H. Westerman, MDb (by invitation), Jeanette T. Thompson, BSNc (by invitation), Meredith A. Weiner, BSNc (by invitation), Ellen L. Cairns, BSNc (by invitation), Benson R. Wilcox, MDa The Journal of Thoracic and Cardiovascular Surgery Volume 109, Issue 2, Pages 224-235 (February 1995) DOI: 10.1016/S0022-5223(95)70383-7 Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 1 Waiting time after listing for patients with CF at University of North Carolina Hospitals, by year. The number of transplantations performed in each calendar year is shown in parentheses. One patient was excluded in 1991 because he was transferred from a heart-lung list with a 3-year wait accumulated. The Journal of Thoracic and Cardiovascular Surgery 1995 109, 224-235DOI: (10.1016/S0022-5223(95)70383-7) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 Actuarial survival (Kaplan-Meier) of patients with CF having double lung transplantation. (Data ± 95% confidence limits.) The Journal of Thoracic and Cardiovascular Surgery 1995 109, 224-235DOI: (10.1016/S0022-5223(95)70383-7) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 3 Actuarial freedom from bronchiolitis obliterans syndrome (BOS) (grades I, II, and III), calculated according to the Kaplan-Meier method. Patients dying of causes other than bronchiolitis obliterans were treated as "withdrawn" for purposes of this analysis. (Data ± 95% confidence limits.) The Journal of Thoracic and Cardiovascular Surgery 1995 109, 224-235DOI: (10.1016/S0022-5223(95)70383-7) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 4 FVC and FEV1 , expressed as percent predicted for CF lung transplant recipients at time of evaluation for transplantation (EVAL) and at intervals after transplantation. (Mean ± standard error of the mean.) The Journal of Thoracic and Cardiovascular Surgery 1995 109, 224-235DOI: (10.1016/S0022-5223(95)70383-7) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 5 Distance walked in 6 minutes at time of evaluation for transplantation (EVAL), after rehabilitation (PRE-TX), and at intervals after transplantation. Improvement in performance was significant at each interval depicted (p < 0.05 by paired Student's t test). The Journal of Thoracic and Cardiovascular Surgery 1995 109, 224-235DOI: (10.1016/S0022-5223(95)70383-7) Copyright © 1995 Mosby, Inc. Terms and Conditions