Typical histopathologic features of CAPNON Typical histopathologic features of CAPNON. A, The typical chondromyxoid matrix of CAPNON (H&E, original magnification ×100). Typical histopathologic features of CAPNON. A, The typical chondromyxoid matrix of CAPNON (H&E, original magnification ×100). B, Focal osseous metaplasia is seen in all 4 cases (H&E, original magnification ×100). C, Medium-power magnification of the chondromyxoid matrix and the peripheral spindle cells (H&E, original magnification ×200). D, Immunohistochemical analysis for EMA demonstrating positive staining in the spindle cells surrounding the matrix (EMA immunohistochemistry, original magnification ×200). A.H. Aiken et al. AJNR Am J Neuroradiol 2009;30:1256-1260 ©2009 by American Society of Neuroradiology