Overall structure of AxqNOR and interhelical dimer interactions

Slides:

Advertisements

Similar presentations

Comparison of ternary TCR-lipid-CD1 complex structures.

Advertisements

The functional and structural basis of phospholipid recognition by the PG90 TCR. The functional and structural basis of phospholipid recognition by the.

Docking footprint of PG90 TCR on CD1b-PG.

Comparison of ternary TCR-lipid-CD1 complex structures.

Fig. 2 Chiral and achiral structures of formic acid.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Evolution of magnetic field lines around a foreshock bubble in the GSE-XY plane (z = 0): Results of a hybrid simulation. Evolution of magnetic field.

Fig. 1 Map of water stress and shale plays.

Fig. 4 Morphogenesis in the Ch-CNC host droplets and NP assemblies.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 6 Comparison of properties of water models.

Fig. 2 TRXSS data. TRXSS data. TRXSS data covering delay times from 10 ns to 10 ms for wild-type DmCry (A), for the DmCry(H378A) mutant (B), and for XlPho.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 1 Cryo-EM structure of yeast Elp123 showing its active site.

Fig. 1 Bioinspired design of AAD for promoting wound contraction.

Fig. 6 External drivers and model response.

Fig. 1 Distribution of total and fake news shares.

Fig. 1 The illustration of discontinuous hydrogen bonding chains in FJU-23-H2O. The illustration of discontinuous hydrogen bonding chains in FJU-23-H2O.

Fig. 2 2D QWs of different propagation lengths.

Fig. 5 Molecular dynamics simulations of Rac1.

Fig. 4 DFT ωB97x/def2-TZVPP atomic charges on the sulfur atom of substituted thioaldehyde and AIMNet prediction with a different number of iterative passes.

Fig. 1 Architecture of the AIMNet model.

Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.

Fig. 2 Assignment of back-exchanged deuterated NaK2K.

Fig. 5 Wave speed analysis.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 4 The mechanical performances of thermally stable click-ionogels.

Fig. 4 Praying Prophet by Lorenzo Monaco: Mapping lake pigments and associated substrate. Praying Prophet by Lorenzo Monaco: Mapping lake pigments and.

Fig. 4 Evolution of fraction of sickled RBCs under hypoxia.

Fig. 1 Structure of the α-SNAP–SNARE subcomplex.

Fig. 2 Magnetic properties of FGT/Pt bilayer.

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 2 Simulations of RBC sickling with a mechanistic model.

Fig. 4 Relationships between light and economic parameters.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Fig. 4 BS-SEM images, ternary diagrams, and phase maps for the text and reverse sides of the TS. BS-SEM images, ternary diagrams, and phase maps for the.

Fig. 1 The calculation of STF moment acceleration, using the 2010 Maule, Chile M8.8 earthquake as an example. The calculation of STF moment acceleration,

Fig. 3 FTIR spectra of plastic standards and sediment samples.

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 Map of δ18OVSMOW in groundwaters of the British Isles (left) and Strontium (87Sr/86Sr) biosphere map of Great Britain (right). Map of δ18OVSMOW.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 3 Information storage substates.

Fig. 4 City sectors ranked by per-industrial output emissions.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Conceptual model of factors that affect treatment effectiveness

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Mapping of abundance of the most dominant bacterial and archaeal phyla across France. Mapping of abundance of the most dominant bacterial and archaeal.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

Fig. 5 Product analog 1,6-hexanediol at the substrate access cavity near the di-iron center and the cavity opening in the MMOH-MMOD complex. Product analog.

Fig. 5 Density plots showing the relationship between growth responses to extreme events and site-level mean precipitation from all sites (N = 1314). Density.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 2 Growth kinetics of borophene on silver.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

The combined signal spectra of PSD for protons and helium nuclei

Fig. 2 Spatial distribution of five city groups.

Fig. 2 Daily TNC pickups and drop-offs for an average Wednesday in fall 2016 (1). Daily TNC pickups and drop-offs for an average Wednesday in fall 2016.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 6 Schematic illustration of the decreased conformational stability in the N92I mutant and its activation mechanism. Schematic illustration of the.

Fig. 1 Crystal structure of the MMOH-MMOD complex.

Fig. 2 Direct and indirect effects of richness, total abundance, and evenness on ecosystem services. Direct and indirect effects of richness, total abundance,

Fig. 4 Orthosteric ligand-binding pocket in CysLT1R.

Fig. 3 Spatial distribution of the shoot density (high densities are represented in dark green and low ones in bright yellow) in a simulation of a P. oceanica.

Fig. 2 Time series of secularization versus GDP per capita, from four illustrative countries, over the 20th century. Time series of secularization versus.

Presentation transcript:

Fig. 1 Overall structure of AxqNOR and interhelical dimer interactions. Overall structure of AxqNOR and interhelical dimer interactions. (A) Dimeric AxqNOR in plane of the lipid bilayer (orange lines) colored by chain (A in teal and B in maroon), with heme groups denoted as purple and cyan sticks. (B) AxqNOR viewed from the periplasmic side showing transmembrane helices numbered with roman numerals, with heme and nonheme iron (FeB) ligating histidines shown as sticks. Calcium is shown as green spheres, and FeB is shown as red spheres. (C) Hydrophobic interactions between TMHII of each respective Val495Ala molecule with the density map contoured at 7σ around the residues, with the wild-type exhibiting a consistent arrangement. Chai C. Gopalasingam et al. Sci Adv 2019;5:eaax1803 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).