Correlation between change in blood pressure (BP) and a rapid annual decline in kidney function (≥3 mL/min/1.73 m2/year) (logistic regression) (n=7283). Correlation between change in blood pressure (BP) and a rapid annual decline in kidney function (≥3 mL/min/1.73 m2/year) (logistic regression) (n=7283). Adjusted for gender, age at baseline, baseline measurements (systolic or diastolic BP or pulse pressure), baseline Charlson Comorbidity Index (CCI), baseline cardiovascular medication, time between the first and last estimated glomerular filtration rate (eGFR) measurement after 2002, baseline eGFR. µAdjusted for interaction term ‘systolic BP change × baseline CCI’ (adjusted OR of the interaction term 1.2 (95% CI 1.0 to 1.3). *Adjusted for interaction term ‘pulse pressure change×baseline pulse pressure’ (adjusted OR of the interaction term 1.3 (95% CI 1.1 to 1.5). Bert Vaes et al. BMJ Open 2015;5:e007571 ©2015 by British Medical Journal Publishing Group