Neighbor joining tree showing relationships between the human cannabinoid CB1 and CB2 receptors and other human rhodopsin α-group type G protein-coupled.

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Neighbor joining tree showing relationships between the human cannabinoid CB1 and CB2 receptors and other human rhodopsin α-group type G protein-coupled receptors. Neighbor joining tree showing relationships between the human cannabinoid CB1 and CB2 receptors and other human rhodopsin α-group type G protein-coupled receptors. The tree was generated using the multiple sequence alignment program ClustalX, with bootstrapping (1000 bootstrap trials), and viewed using NJ plot. The tree shows receptors that are discussed in section IV.A of this review; the muscarinic acetylcholine receptors M1–M5 are included as an outgroup. R. G. Pertwee et al. Pharmacol Rev 2010;62:588-631 Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics