Jenner's Irony: Cowpox Taps into T Cell Evasion

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Presentation transcript:

Jenner's Irony: Cowpox Taps into T Cell Evasion Gavin W.G. Wilkinson, Paul J. Lehner Cell Host & Microbe Volume 6, Issue 5, Pages 395-397 (November 2009) DOI: 10.1016/j.chom.2009.11.001 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Cowpox Inhibits MHC Class I Antigen Processing CPXV12 acts as a TAP inhibitor to prevent peptide loading onto MHC class I in the ER. The CPXV203 protein contains an ER-retention signal that is instrumental in promoting retrieval and recycling of MHC class I from the Golgi. A portrait of Edward Jenner is shown above the model. Cell Host & Microbe 2009 6, 395-397DOI: (10.1016/j.chom.2009.11.001) Copyright © 2009 Elsevier Inc. Terms and Conditions