Profile of diastolic function parameters at rest, immediately post-exercise and into recovery. Profile of diastolic function parameters at rest, immediately post-exercise and into recovery. (A) A significant elevation in septal E/e′ with exercise and into recovery in patients with diabetes mellitus (DM), while septal E/e′ remains normal for non-DM. (B) A similar pattern of rise and fall in mitral inflow E wave velocity with exercise in both groups. (C) An increase in septal e′ in both groups; however, this is significantly more for non-DM. Melissa Leung et al. Open Heart 2015;2:e000214 ©2015 by British Cardiovascular Society