HMQ1611 inhibited breast tumor growth in mice. HMQ1611 inhibited breast tumor growth in mice. A, the representative images of breast tumors (top) and immunostaining of ERα expression (bottom) using anti-ERα antibodies from each experimental group at the end point. B, quantification of ERα expression from 6 random fields of each section, 3 sections from each animal. Results were quantified using an image analysis system. Data are represented as means ± SEM. *, P < 0.05; **, P < 0.01 by ANOVA compared with the vehicle-treated control group. Yingzhuan Zhan et al. Cancer Prev Res 2012;5:864-873 ©2012 by American Association for Cancer Research