Patient Tregs express normal levels of suppression.

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Presentation transcript:

Patient Tregs express normal levels of suppression. Patient Tregs express normal levels of suppression. CD4+CD25+ Tregs were immunopurified from PBMCs and assessed for their capacity to suppress the proliferation of autologous CD4+CD25- cells at a responder/Treg ratio of 1:1. Percent inhibition of responder cell proliferation due to the presence of Tregs was measured using 17 samples collected from 5 cGVHD patients, 7 patients without cGVHD, and 5 healthy individuals. The solid lines represent the median values. Emmanuel Zorn et al. Blood 2005;106:2903-2911 ©2005 by American Society of Hematology