International Journal of Cardiology

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International Journal of Cardiology Top ten risk factors for morbidity and mortality in patients with chronic systolic heart failure and elevated heart rate: The SHIFT Risk Model Ian Ford, Michele Robertson, Michel Komajda, Michael Böhm, Jeffrey S. Borer, Luigi Tavazzi, Karl Swedberg International Journal of Cardiology Volume 184, Pages 163-169 (April 2015) DOI: 10.1016/j.ijcard.2015.02.001 Copyright © 2015 The Authors Terms and Conditions

Fig. 1 Observed and predicted risk for primary outcome (A), all-cause mortality (B), cardiovascular mortality (C), and heart failure (HF) hospitalisation (D) by tenths of the distribution of predicted risk (approach excluding baseline therapies). International Journal of Cardiology 2015 184, 163-169DOI: (10.1016/j.ijcard.2015.02.001) Copyright © 2015 The Authors Terms and Conditions

Fig. 2 Kaplan–Meier time to primary endpoint plots for patients split by fifths of the distribution of risk separately in the ivabradine and placebo groups (patients in the highest fifth are at highest baseline risk) for the model including therapies. International Journal of Cardiology 2015 184, 163-169DOI: (10.1016/j.ijcard.2015.02.001) Copyright © 2015 The Authors Terms and Conditions

Fig. 3 Hazard ratios and 95% confidence intervals for the effect of ivabradine versus placebo on the primary endpoint by fifths of the distribution of baseline risk (denoted by F1 to F5, with F5 being the highest risk), based on the best 10 models including baseline therapies. International Journal of Cardiology 2015 184, 163-169DOI: (10.1016/j.ijcard.2015.02.001) Copyright © 2015 The Authors Terms and Conditions