Tivantinib behaves as an antimitotic agent.

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Genomic signatures to guide the use of chemotherapeutics Authors: Anil Potti et. al Presenter: Jong Cheol Jeong.

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Presentation transcript:

Tivantinib behaves as an antimitotic agent. Tivantinib behaves as an antimitotic agent. A, Scatter plots showing correlations between sensitivity patterns assessed by the AUC of two antimitotic drugs (paclitaxel and vinblastine) and tivantinib among 35 liver cancer cell lines. B, Effect of tivantinib on the mitotic index was compared with the antimitotic drugs paclitaxel and vinblastine after overnight treatment of the HLE cell line with two different concentrations of each drug. Sandra Rebouissou et al. Clin Cancer Res 2017;23:4364-4375 ©2017 by American Association for Cancer Research