post intervention (n=60) Table 3. Mean knowledge scores of the studied clients regarding systemic lupus erythematous disease pre and post intervention (n=60) Knowledge Score Pre-intervention Post-intervention Paired t test P value Mean ±SD Definition of systemic lupus 1 .6500±.48099 .8500±.36008 -2.352 <0.05* Causes of systemic lupus .4333±.49972 -5.217 <0.001** Risk factors of systemic lupus 2 .5500±.50169 1.6667±.47538 -14.106 Signs and symptoms of systemic lupus 7 2.9167±1.38137 5.9333±.77824 -13.726 Diagnostic tests of systemic lupus 4 1.9500±.69927 3.7333±.44595 -17.171 Treatment of systemic lupus 2.2667±.73338 3.8167±.39020 -15.192 Complications of systemic lupus 11 5.8333±1.32980 10.0000±.86358 -18.776 Total knowledge 30 14.6000±2.38071 26.8500±1.77387 -33.790 * Statistically significant difference (p≤0.05), **Highly statistically significant difference (p≤0.001). Doaa Mohamed Sobhy Elsayed et al. Effect of Health Education based Intervention on Self-care among Systemic Lupus Erythematosus Clients. American Journal of Nursing Research, 2018, Vol. 6, No. 3, 105-112. doi:10.12691/ajnr-6-3-4 © The Author(s) 2018. Published by Science and Education Publishing.