Hyperplastic alveolar epithelial type II cells show severe endoplasmic reticulum stress and consecutive apoptosis. Hyperplastic alveolar epithelial type.

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Hyperplastic alveolar epithelial type II cells show severe endoplasmic reticulum stress and consecutive apoptosis. Hyperplastic alveolar epithelial type II cells show severe endoplasmic reticulum stress and consecutive apoptosis. Representative immunohistochemistry for a, d) pro-surfactant protein C, b) cleaved caspase 3, c) C/EBP homologous protein, e) activating transcription factor (ATF)-6 and f) ATF-4 in serial sections of idiopathic pulmonary fibrosis lung tissue. Scale bars=50 µm. Reproduced from [10] with permission from the publisher. Andreas Günther et al. Eur Respir Rev 2012;21:152-160 ©2012 by European Respiratory Society