Kaplan-Meier survival (renal event-free) curves during follow-up by tertiles of plasma copeptin. Kaplan-Meier survival (renal event-free) curves during follow-up by tertiles of plasma copeptin. Renal events were defined as the doubling of the serum creatinine levels or ESRD during follow-up. A: Subjects with microalbuminuria or macroalbuminuria at baseline (n = 3,101). B: Subjects with macroalbuminuria at baseline (n = 729). Gilberto Velho et al. Dia Care 2013;36:3639-3645 ©2013 by American Diabetes Association