Superficial temporal artery aneurysm associated with immunoglobulin G4-related disease Sosei Kuma, MD, PhD, Tsubasa Takeshima, MD, Takefumi Ohga, MD,

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Presentation transcript:

Superficial temporal artery aneurysm associated with immunoglobulin G4-related disease Sosei Kuma, MD, PhD, Tsubasa Takeshima, MD, Takefumi Ohga, MD, PhD, Tadahiro Nozoe, MD, PhD, Katsuo Sueishi, MD, PhD Journal of Vascular Surgery Cases and Innovative Techniques Volume 3, Issue 4, Pages 243-246 (December 2017) DOI: 10.1016/j.jvscit.2017.10.005 Copyright © 2017 The Author(s) Terms and Conditions

Fig 1 Computed tomography images obtained on admission. A, Computed tomography angiography showing superficial temporal artery (STA) aneurysm. The STA was tortuous. B, Axial image showing STA aneurysm. C, Coronal image showing STA aneurysm. The arrows indicate the STA aneurysm. Journal of Vascular Surgery Cases and Innovative Techniques 2017 3, 243-246DOI: (10.1016/j.jvscit.2017.10.005) Copyright © 2017 The Author(s) Terms and Conditions

Fig 2 Pathologic findings of superficial temporal artery (STA) aneurysm. Histologic sections show the marked and eccentric intimal thickening, regenerative and hyperplastic muscle layer with frequent destruction of elastic membranes, marked adventitial fibrosis in a multilayer pattern, and inflammatory infiltrate, including follicle-like aggregations of lymphocytes. On immunoglobulin G4 (IgG4) immunohistochemistry, IgG4-positive lymphocytes were scattered in the adventitia, and the distribution of IgG4-positive lymphocytes met the histopathologic criteria of IgG4-related disease (IgG4-RD). A, Hematoxylin-eosin stain (×20). B, Hematoxylin-eosin stain (×100). C, Elastic-van Gieson stain (×100). D, Anti-IgG4 stain (×100). Journal of Vascular Surgery Cases and Innovative Techniques 2017 3, 243-246DOI: (10.1016/j.jvscit.2017.10.005) Copyright © 2017 The Author(s) Terms and Conditions

Fig 3 Computed tomography images obtained on admission. Serial axial images show wall thickening and enhancement on the anterior and left wall of the infrarenal abdominal aorta. Journal of Vascular Surgery Cases and Innovative Techniques 2017 3, 243-246DOI: (10.1016/j.jvscit.2017.10.005) Copyright © 2017 The Author(s) Terms and Conditions