Cytogenetic Profile of Lymphoma of Follicle Mantle Lineage: Correlation With Clinicobiologic Features by Antonio Cuneo, Renato Bigoni, Gian Matteo Rigolin,

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Cytogenetic Profile of Lymphoma of Follicle Mantle Lineage: Correlation With Clinicobiologic Features by Antonio Cuneo, Renato Bigoni, Gian Matteo Rigolin, Maria Grazia Roberti, Antonella Bardi, Nadia Piva, Raffaella Milani, Florencia Bullrich, Maria Luisa Veronese, Carlo Croce, Françoise Birg, Hartmut Döhner, Anne Hagemeijer, and Gianluigi Castoldi Blood Volume 93(4):1372-1380 February 15, 1999 ©1999 by American Society of Hematology

BCL1 rearranged leukemic MCL with primary BM involvement. BCL1 rearranged leukemic MCL with primary BM involvement. Note the heterogeneity of cell size and morphology with irregular nuclear outline (left). A cell showing juxtaposition (arrowed) of BCL1 (green) to IgH (red) sequences is shown on the right. Antonio Cuneo et al. Blood 1999;93:1372-1380 ©1999 by American Society of Hematology

Survival according to the presence (n = 12) or absence (n = 30) of total/partial trisomy 12 (P .006). Survival according to the presence (n = 12) or absence (n = 30) of total/partial trisomy 12 (P .006). Antonio Cuneo et al. Blood 1999;93:1372-1380 ©1999 by American Society of Hematology

Survival according to the degree of karyotype complexity as defined by CCA + FISH analysis (group 1 = 11 patients; group 2 = 14 patients; group 3 = 17 patients) (P < .0001). Survival according to the degree of karyotype complexity as defined by CCA + FISH analysis (group 1 = 11 patients; group 2 = 14 patients; group 3 = 17 patients) (P < .0001). Antonio Cuneo et al. Blood 1999;93:1372-1380 ©1999 by American Society of Hematology