Volume 96, Issue 1, Pages 5-7 (July 2019)

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Volume 96, Issue 1, Pages 5-7 (July 2019) Journal Club Kidney International Volume 96, Issue 1, Pages 5-7 (July 2019) DOI: 10.1016/j.kint.2019.05.001 Copyright © 2019 Terms and Conditions

Figure 1 Survival curves of CAR T–treated and control MRL-lpr mice. From Kansal R, Richardson N, Neeli I, et al. Sustained B cell depletion by CD19-targeted CAR T cells is a highly effective treatment for murine lupus. Sci Transl Med. 2019;11(482). Reprinted with permission from AAAS. Kidney International 2019 96, 5-7DOI: (10.1016/j.kint.2019.05.001) Copyright © 2019 Terms and Conditions

Figure 2 Reduced glomerular size and inflammation (hematoxylin and eosin [H&E]) and IgG deposits (immunofluorescence [IF]) in CAR T-cell–treated NZB/W mice. From Kansal R, Richardson N, Neeli I, et al. Sustained B cell depletion by CD19-targeted CAR T cells is a highly effective treatment for murine lupus. Sci Transl Med. 2019;11(482). Reprinted with permission from AAAS. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org. Kidney International 2019 96, 5-7DOI: (10.1016/j.kint.2019.05.001) Copyright © 2019 Terms and Conditions