Bio-AMS enhances the activity of rifampicin and ethambutol in vitro

Slides:



Advertisements
Similar presentations
Bio-AMS enhances the activity of rifampicin and ethambutol in vitro
Advertisements

Fig. 1 Chemical inactivation of BPL kills Mtb and prevents growth in mouse macrophages. Chemical inactivation of BPL kills Mtb and prevents growth in mouse.
Fig. 5 MicroLED array with 3D liquid metal interconnects.
Fig. 2 Transport properties of a BP transistor at low temperature.
Fig. 4 Ballistic simulation of BP FETs.
Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.
Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,
Fig. 4 INS spectra of different human bones from the Roman period [humerus, ulna, femur, and fibula from the same skeleton, Guidonia-Montecelio, Italy.
Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)
Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.
Fig. 1 Map of water stress and shale plays.
In vivo release of doxycycline hyclate from the GRS in a swine model
Fig. 1 Examples of experimental stimuli and behavioral performance.
Fig. 3 Electron PSD in various regions.
Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.
Fig. 2 Fabrication and in vitro release of TB antibiotics from individual drug pills. Fabrication and in vitro release of TB antibiotics from individual.
Fig. 6 Comparison of properties of water models.
Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.
Fig. 2 Reference-fixing experiment, results.
Fig. 3 Scan rate effects on the layer edge current.
Fig. 2 Stratigraphic profile of the Area 15 excavation block showing the diagnostic cultural materials and components alongside the stratigraphic sequence.
Fig. 3 Rotation experiment, setup.
Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.
FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)
Fig. 1 Schematic illustration of the preparation and potential application of FMSMs. Schematic illustration of the preparation and potential application.
BMS blocks functional responses in primary immune cells driven by IFNα
Fig. 6 SNP rs is a functional SNP in 22Rv1 cells.
Fig. 1 Distribution of total and fake news shares.
Fig. 2 2D QWs of different propagation lengths.
Fig. 6 WPS imaging of different chemical components in living cells.
Fig. 4 DFT ωB97x/def2-TZVPP atomic charges on the sulfur atom of substituted thioaldehyde and AIMNet prediction with a different number of iterative passes.
Fig. 5 Simultaneous absence of caspase-3 and -7 is required for significant decrease of caspase-8 and -9 activation in intrinsic apoptosis. Simultaneous.
Fig. 3 ET dynamics on the control and treatment watersheds during the pretreatment and treatment periods. ET dynamics on the control and treatment watersheds.
Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.
Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.
Fig. 4 OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with different pH. OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with.
Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.
Fig. 4 The mechanical performances of thermally stable click-ionogels.
Fig. 1 Cross-sectional images of He-implanted V/Cu/V samples.
Fig. 1 Time course of growth parameters for acetate-grown cultures of M. acetivorans with and without supplements. Time course of growth parameters for.
Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.
Fig. 2 Schematic drawings of Göbekli Tepe skulls.
Fig. 4 SPICE simulation of stochasticity.
Fig. 1 Size fractions of MPPs in different fertilizers.
Fig. 2 Sampling. Sampling. (A) Extant stratigraphic section. Zenithal (B) and frontal (C) views of the flowstone capping the excavated deposit. The rectangle.
Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.
Schematic of the proposed brain-controlled assistive hearing device
Fig. 5 Skull 1: Tentative reconstruction.
Fig. 6 Experimental setup and properties of the IP screen.
Fig. 3 FTIR spectra of plastic standards and sediment samples.
Fig. 1 Location of the Jirzankal Cemetery.
Fig. 4 Map of δ18OVSMOW in groundwaters of the British Isles (left) and Strontium (87Sr/86Sr) biosphere map of Great Britain (right). Map of δ18OVSMOW.
Fig. 2 6-HAP does not inhibit DNA synthesis in vitro.
Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.
Experimenter gender and replicability in science
Fig. 1 Effects of experimental warming on nematode communities across the gradient of plant species richness. Effects of experimental warming on nematode.
Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.
Fig. 4 Mapping of abundance of the most dominant bacterial and archaeal phyla across France. Mapping of abundance of the most dominant bacterial and archaeal.
Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.
Fig. 1 Chemical structures of the bioconjugates.
Fig. 4 Single-particle contact angle measurements.
Fig. 2 Supraballs and films from binary SPs.
Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.
Fig. 4 Behavior of resistance peak near density nm = 5.
Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.
Fig. 2 Daily TNC pickups and drop-offs for an average Wednesday in fall 2016 (1). Daily TNC pickups and drop-offs for an average Wednesday in fall 2016.
Fig. 4 Effects of individual picosecond and microsecond pulses.
Fig. 3 Calculated electronic structure of ZrCoBi.
Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.
Fig. 2 Time series of secularization versus GDP per capita, from four illustrative countries, over the 20th century. Time series of secularization versus.
Presentation transcript:

Fig. 5 Bio-AMS enhances the activity of rifampicin and ethambutol in vitro. Bio-AMS enhances the activity of rifampicin and ethambutol in vitro. (A to E) Impact of Bio-AMS on the activities of the TB drugs rifampicin (A and D), ethambutol (B and E), and isoniazid (C). The Mtb H37Rv strain was grown in standard liquid culture with Bio-AMS (1 μM in DMSO) or DMSO alone for 3 days, after which the bacteria were exposed to the other anti-TB drugs. Data are representative of two independent experiments with three samples per time point. Data are means ± SEM. Divya Tiwari et al., Sci Transl Med 2018;10:eaal1803 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).