A decision matrix for readers, reviewers, and guideline makers to conceptualize results-based and process-based merits in clinical trials. A decision matrix.

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Presentation transcript:

A decision matrix for readers, reviewers, and guideline makers to conceptualize results-based and process-based merits in clinical trials. A decision matrix for readers, reviewers, and guideline makers to conceptualize results-based and process-based merits in clinical trials. Studies that have high results-based merit are characterized by narrow CIs and may or may not reject H0. Their level of acceptability, particularly in high impact journals, should be viewed through the lens of process-based merit. On the other hand, studies that are characterized by both low results-based and process-based merit are frequently rejected. Ajay K. Singh et al. CJASN 2008;3:1246-1252 ©2008 by American Society of Nephrology