Fig. 5 Enzyme activity of PE-DNase I/Pt tuned by changing temperature or NIR light. Enzyme activity of PE-DNase I/Pt tuned by changing temperature or NIR light. (A) Illustration shows that PE-DNase I/Pt catalyzes the degradation of plasmid DNA. (B) Agarose gel electrophoresis of plasmid PX330 after different treatments. M means DNA marker. (C and D) Relative fold increase of PE-DNase I and PE-DNase I/Pt activities by heating in water bath (45°C) or exposure to NIR light (3.8 W cm−2, 20 min). ***P < 0.001 analyzed by Student’s t test (n = 3). Song Zhang et al. Sci Adv 2019;5:eaaw4252 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).