Kaplan–Meier analysis of PFS and OS in patients with advanced non-small cell lung cancer with adenocarcinoma histology with time since start of first-line therapy <9 months. Kaplan–Meier analysis of PFS and OS in patients with advanced non-small cell lung cancer with adenocarcinoma histology with time since start of first-line therapy <9 months. (A) Centrally assessed PFS (primary analysis) in patients treated in LUME-Lung 2, (B) centrally assessed PFS (primary analysis) and (C) final OS in patients treated in LUME-Lung 1. OS, overall survival; PFS, progression-free survival. Birgit Gaschler-Markefski et al. ESMO Open 2017;2:e000102 Copyright © European Society for Medical Oncology. All rights reserved.